Aggressive undifferentiated small round cell sarcoma of the thorax showing TOP2B::UBA3 fusion.

This article reports on a case of an aggressive undifferentiated small round cell sarcoma of the thorax that showed a fusion between the TOP2B and UBA3 genes. This type of sarcoma has not been reported previously. The patient, a 64-year-old woman, presented with back pain and was diagnosed with a malignant round cell tumor. Despite treatment with chemotherapy, the tumor continued to grow, and the patient eventually chose best supportive care. The article provides a detailed description of the tumor's characteristics and discusses the potential implications of the TOP2B::UBA3 fusion. [Extracted from the article]