Proliferative glomerulonephritis with monoclonal immunoglobulin deposits in the native or posttransplant kidney.

This document provides a summary of a study on proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID), a kidney disease characterized by the presence of a monoclonal immunoglobulin. The study analyzed 15 patients with PGNMID in Belgium and The Netherlands and provided detailed information on patient demographics, kidney function, biopsy findings, and treatment regimens. The study found that patients who received clone-directed therapy had a better renal response compared to those who did not. Recurrence of PGNMID after kidney transplantation was common, and the study calls for further research to improve diagnostic and therapeutic strategies for this disease. [Extracted from the article]