Time‐dependent in vitro variations of platelet count in samples from subjects with EDTA‐induced pseudothrombocytopenia: A comparative analysis across different anticoagulants.

This article discusses the phenomenon of pseudothrombocytopenia (PTP), which refers to falsely low platelet counts in blood samples due to platelet agglutination during sample storage. The study compared the accuracy and stability of platelet counts in PTP subjects using different anticoagulants and storage times. The results showed that K3EDTA was the most reliable anticoagulant for immediate platelet counting, while alternative anticoagulants were better at stabilizing platelet counts over time. However, all anticoagulants were unable to prevent a time-dependent decrease in platelet count in some samples, leading to thrombocytopenia. The study suggests that microscopic examination of blood samples is still necessary to confirm platelet counts in PTP subjects. [Extracted from the article]