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CyclicPepedia: a knowledge base of natural and synthetic cyclic peptides.
- Source :
- Briefings in Bioinformatics; May2024, Vol. 25 Issue 3, p1-11, 11p
- Publication Year :
- 2024
-
Abstract
- Cyclic peptides offer a range of notable advantages, including potent antibacterial properties, high binding affinity and specificity to target molecules, and minimal toxicity, making them highly promising candidates for drug development. However, a comprehensive database that consolidates both synthetically derived and naturally occurring cyclic peptides is conspicuously absent. To address this void, we introduce CyclicPepedia (https://www.biosino.org/iMAC/cyclicpepedia/), a pioneering database that encompasses 8744 known cyclic peptides. This repository, structured as a composite knowledge network, offers a wealth of information encompassing various aspects of cyclic peptides, such as cyclic peptides' sources, categorizations, structural characteristics, pharmacokinetic profiles, physicochemical properties, patented drug applications, and a collection of crucial publications. Supported by a user-friendly knowledge retrieval system and calculation tools specifically designed for cyclic peptides, CyclicPepedia will be able to facilitate advancements in cyclic peptide drug development. [ABSTRACT FROM AUTHOR]
- Subjects :
- CYCLIC peptides
PEPTIDOMIMETICS
KNOWLEDGE base
DRUG patents
PATENT applications
Subjects
Details
- Language :
- English
- ISSN :
- 14675463
- Volume :
- 25
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Briefings in Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 177375815
- Full Text :
- https://doi.org/10.1093/bib/bbae190