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Randomized controlled trial of an Acceptance and Commitment Therapy and compassion-based group intervention for persons with inflammatory bowel disease: the LIFEwithIBD intervention.

Authors :
Ferreira, Cláudia
Pereira, Joana
Skvarc, David
Oliveira, Sara
Galhardo, Ana
Ferreira, Nuno B.
Lucena-Santos, Paola
Carvalho, Sérgio A.
Matos-Pina, Inês
Rocha, Bárbara S.
Portela, Francisco
Trindade, Inês A.
Source :
Frontiers in Psychology; 2024, p01-12, 12p
Publication Year :
2024

Abstract

Objectives: This study tested the acceptability and efficacy of an Acceptance and Commitment Therapy and compassion-based intervention (LIFEwithIBD) in people with IBD through a two-arm RCT. Methods: Participants were recruited at the Gastroenterology Department of the Coimbra University Hospital between June and September 2019. Of the 355 patients screened, those who accepted to participate were randomly assigned to one of two conditions: experimental group (LIFEwithIBD; n = 25) or control group (waitlist; n = 29). Participants completed self-report measures at baseline (T0), post-intervention (T1), and 3-month (T2) and 12-month (T3) follow-ups. Intervention acceptability was assessed. Efficacy was examined using intent-to-treat ANCOVA at post-intervention after adjusting for baseline values of depressive, anxiety, and stress symptoms (primary outcomes). Linear mixed models for all longitudinal outcomes were also analysed. Inflammatory and disease biomarkers were determined at T0 and T3. Results: Acceptability results revealed a high level of satisfaction and perceived usefulness regarding the intervention. Both groups experienced a significant decrease in stress symptoms and IBD symptom perception at T1. No significant differences were observed at follow-up for the primary outcomes. The experimental group reported significantly lower Crohn's disease Symptom severity at T2 than the control group. Post-hoc analyses designed to mitigate floor effects revealed substantial treatment effects for the experimental group regarding anxiety symptoms. No significant differences were observed in clinical biomarkers from T0 to T3. Conclusion: The LIFEwithIBD intervention shows promising, although preliminary, benefits for managing disease activity and reducing anxiety symptoms in IBD patients with high severity of psychological distress. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16641078
Database :
Complementary Index
Journal :
Frontiers in Psychology
Publication Type :
Academic Journal
Accession number :
177411912
Full Text :
https://doi.org/10.3389/fpsyg.2024.1367913