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Correlation of non-invasive parameters with upper gastrointestinal endoscopy findings for presence and grading of gastroesophageal varices in liver cirrhosis patients.

Authors :
Mathur, Navgeet
Patel, Harsh
Mangalia, Ravi
Mehta, Amit
Mathur, Medha
Verma, Anjana
Patyal, Ashish
Source :
Journal of Family Medicine & Primary Care; Apr2024, Vol. 13 Issue 4, p1347-1353, 7p
Publication Year :
2024

Abstract

Background: Development of esophageal varices is one of the major complications of liver cirrhosis, and endoscopy is used to see the presence, grading, and long-term monitoring of esophageal varices which is an invasive and unpleasant procedure. There is no adequate data available showing noninvasive methods can be used for the same. Methods: Seventy patients with liver cirrhosis participated in the study. Factors like portal vein diameter, spleen size, platelet count, serum bilirubin, Child-Pugh score, prothrombin time (PT), and PT INR were observed and correlated endoscopically with the presence and grading of esophageal varices in all patients. Results: The platelet count, portal vein diameter, serum bilirubin, spleen bipolar diameter, and PT had statistically significant correlations with the presence of varices. Among them, platelet count, portal vein diameter, and serum bilirubin also had statistically significant correlations with the grading of varices. Monitoring of these noninvasive parameters can help in monitoring variceal growth. Conclusions: Noninvasive parameters can be used effectively to predict the presence and grading of esophageal varices and at the same time keep the rate of undiagnosed varices acceptably low. By using noninvasive parameters, patients can be benefited by decreasing the requirement of repeated endoscopic evaluation which is an unpleasant procedure and availability is also limited. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22494863
Volume :
13
Issue :
4
Database :
Complementary Index
Journal :
Journal of Family Medicine & Primary Care
Publication Type :
Academic Journal
Accession number :
177472157
Full Text :
https://doi.org/10.4103/jfmpc.jfmpc_702_23