Clinical research nurses perceive their role as being like the hub of a wheel without real power: Empirical qualitative research.

Aim: This study aimed to explore the experiences of being a clinical research nurse (CRN), in Sweden. Design: A qualitative study analysing individual interview data. Methods: Interviews with 10 participants were conducted in April 2017 and repeated with five participants in May 2022. A semi‐structured interview guide was used to cover topics such as experiences of working in a new role and professional challenges related to the role. The transcribed interviews were analysed inductively using qualitative content analysis. Results: The main theme revealed that the CRNs experienced their work role as being like a hub in a wheel, using an ethical compass, but without real power. The six themes identified showed that CRNs worked independently and relied on clinical experiences as nurses but needed more education. They not only had a sense of duty but also too large responsibilities. Furthermore, they viewed their work as valuable and important. However, they needed an accentuated ethical compass and were also affected by power relations that negatively impacted work. Conclusion: Working as a CRN means being in a central position and working independently, which requires diverse skills and competencies. CRNs, however, face and manage complex ethical and practical challenges without real power. They experience huge responsibilities but need education and acknowledgement, indicating a need for improvement. This is an important message to stakeholders and managers about the necessity of taking adequate action to support CRNs who are crucial resources in clinical research. Patient or Public Contribution: No patient or public contribution. [ABSTRACT FROM AUTHOR]