Back to Search Start Over

Treatment Revolution: The New Era Against Hepatitis C.

Authors :
Gavril, Oana Irina
Eșanu, Irina Mihaela
Gavril, Radu Sebastian
Buruiană, Carmen Camelia
Mitu, Florin
Source :
Internal Medicine / Medicină Internă; Jun2024, Vol. 21 Issue 2, p79-84, 6p
Publication Year :
2024

Abstract

In recent decades, chronic viral infection C (HCV) has posed a major public health challenge globally, considering the morbidity and mortality associated with this condition, as well as the difficulties related to diagnosis and treatment. Recently, significant advances in medical and pharmaceutical research have led to the development of new direct-acting antiviral therapies (DAAs), marking the beginning of a new era in HCV treatment. These treatments promise cure rates of over 90%, an improved safety profile, and a reduced duration of therapy compared to previous interferon-based regimens. This article aims to examine the evolution of HCV treatment, with a special focus on recent innovations in antiviral therapy. We will analyze the mechanisms of action of DAAs, their efficacy and safety, and their impact on populations with limited access to treatment. Additionally, we discuss the remaining challenges in the path to HCV eradication, including late diagnosis, barriers to treatment access, and the need for long-term monitoring of cured patients. By consolidating data from recent clinical studies and reviewing the specialized literature, this article provides a comprehensive perspective on the current landscape of HCV treatment, highlighting significant progress made and underlining the future directions needed to address remaining challenges. Finally, we reaffirm the importance of an integrated approach, encompassing prevention, early diagnosis, and universal access to innovative treatments, as a cornerstone in the fight against HCV. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
12205818
Volume :
21
Issue :
2
Database :
Complementary Index
Journal :
Internal Medicine / Medicină Internă
Publication Type :
Academic Journal
Accession number :
177820121
Full Text :
https://doi.org/10.2478/inmed-2024-0290