New Findings on Dengue Hemorrhagic Fever from Jamia Hamdard Summarized (Paper-based Aptasensor for Electrochemical Detection of Polyvalent Antigen of Dengue Virus).

A recent report from Jamia Hamdard in New Delhi, India, discusses the development of a paper-based aptasensor for the detection of all serotypes of the Dengue virus (DENV). The aptasensor is simple, low-cost, reproducible, and disposable, making it suitable for point-of-care diagnostic applications. The research team used a three-electrode system with a silver/zinc nanocomposite as the working electrode and employed aptamers to enhance the sensor's functioning. The aptasensor demonstrated a broad linear range of 0.1-1000 μg/ml for the DENV virus, with a limit of detection of 0.1 μg/ml. This research provides a sensitive and cost-effective diagnostic tool for detecting multiple serotypes of DENV, particularly in rural areas with limited resources. [Extracted from the article]