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CASCADE: Context-Aware Data-Driven AI for Streamlined Multidisciplinary Tumor Board Recommendations in Oncology.
- Source :
- Cancers; Jun2024, Vol. 16 Issue 11, p1975, 8p
- Publication Year :
- 2024
-
Abstract
- Simple Summary: This research aims to evaluate the effectiveness of a machine learning algorithm, XGBoost, in predicting treatment recommendations for patients with hepatocellular carcinoma (HCC). The study uses clinical and imaging data from patients discussed at a multidisciplinary tumor board. The findings suggest that the algorithm can accurately predict all eight treatment recommendations made by the board, potentially aiding clinical decision-making in settings lacking subspecialty expertise. This study addresses the potential of machine learning in predicting treatment recommendations for patients with hepatocellular carcinoma (HCC). Using an IRB-approved retrospective study of patients discussed at a multidisciplinary tumor board, clinical and imaging variables were extracted and used in a gradient-boosting machine learning algorithm, XGBoost. The algorithm's performance was assessed using confusion matrix metrics and the area under the Receiver Operating Characteristics (ROC) curve. The study included 140 patients (mean age 67.7 ± 8.9 years), and the algorithm was found to be predictive of all eight treatment recommendations made by the board. The model's predictions were more accurate than those based on published therapeutic guidelines by ESMO and NCCN. The study concludes that a machine learning model incorporating clinical and imaging variables can predict treatment recommendations made by an expert multidisciplinary tumor board, potentially aiding clinical decision-making in settings lacking subspecialty expertise. [ABSTRACT FROM AUTHOR]
- Subjects :
- MEDICAL protocols
RECEIVER operating characteristic curves
PREDICTION models
DATABASE management
ARTIFICIAL intelligence
ONCOLOGY
RETROSPECTIVE studies
DECISION making in clinical medicine
DESCRIPTIVE statistics
MEDICAL records
ACQUISITION of data
ARTIFICIAL neural networks
MACHINE learning
ALGORITHMS
HEPATOCELLULAR carcinoma
HEALTH care teams
Subjects
Details
- Language :
- English
- ISSN :
- 20726694
- Volume :
- 16
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Cancers
- Publication Type :
- Academic Journal
- Accession number :
- 177874053
- Full Text :
- https://doi.org/10.3390/cancers16111975