Patent Issued for Compositions and methods for inducing scarring by peri-tumoral cells (USPTO 11998614).

Duke University has been issued a patent for compositions and methods for inducing scarring by peri-tumoral cells. The patent aims to develop improved methods for treating brain tumors, specifically gliomas, which are highly invasive and difficult to access. The technology involves targeting and activating peri-tumoral cells with a stimulus that mimics the effects of a traumatic central nervous system injury, creating a barrier that inhibits tumor growth and spread. The compositions include nanoparticles and ligands that activate peri-tumoral cells to induce scarring. This patent offers potential advancements in the treatment of brain tumors and gliomas. [Extracted from the article]