Patent Issued for Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing (USPTO 12006532).

The University of Washington has been issued a patent for methods of targeted nucleic acid sequence enrichment, specifically in error-corrected nucleic acid sequencing. This technology aims to improve the accuracy and efficiency of sequencing genetic material, particularly in forensic analysis. The methods involve using uniquely labeled strands in a double-stranded nucleic acid complex to enable error correction during sequencing. This technology has the potential to enhance the detection of genetic variants and mutations in small amounts of nucleic acid material. The patent describes methods for targeted nucleic acid sequence enrichment and error-corrected nucleic acid sequencing, which can be used for sequencing targets of interest, such as DNA fragments from subjects or liquid biopsy samples. The patent was filed by Michael Hipp from the University of Washington. [Extracted from the article]