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Inbred Mouse Models in Cryptococcus neoformans Research.
- Source :
- Journal of Fungi; Jun2024, Vol. 10 Issue 6, p426, 17p
- Publication Year :
- 2024
-
Abstract
- Animal models are frequently used as surrogates to understand human disease. In the fungal pathogen Cryptococcus species complex, several variations of a mouse model of disease were developed that recapitulate different aspects of human disease. These mouse models have been implemented using various inbred and outbred mouse backgrounds, many of which have genetic differences that can influence host response and disease outcome. In this review, we will discuss the most commonly used inbred mouse backgrounds in C. neoformans infection models. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 2309608X
- Volume :
- 10
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Journal of Fungi
- Publication Type :
- Academic Journal
- Accession number :
- 178194283
- Full Text :
- https://doi.org/10.3390/jof10060426