Studies from Ahram Canadian University Add New Findings in the Area of Pseudomonas aeruginosa (In Vivo and in Vitro activity of colistin-conjugated bimetallic silver-copper oxide nanoparticles against Pandrug-resistant Pseudomonas aeruginosa).

A recent study conducted at Ahram Canadian University explored the use of colistin-conjugated bimetallic silver-copper oxide nanoparticles as a potential treatment for pandrug-resistant Pseudomonas aeruginosa. The nanoparticles were synthesized using gamma rays and characterized through various analytical methods. The study found that the nanoparticles exhibited antimicrobial activity against P. aeruginosa, reduced the minimum inhibitory concentration of colistin, and inhibited virulence factors such as pyocyanin production and biofilm formation. The nanoparticles were also found to be non-toxic in a Galleria mellonella model. Further research is needed to understand the mechanisms underlying the inhibitory effects of these nanoparticles. [Extracted from the article]