Researchers from Nankai University Detail New Studies and Findings in the Area of Cancer (Multifunctional Dna Nanoflower Applied for High Specific Photodynamic Cancer Therapy in Vivo).

Researchers from Nankai University in Tianjin, China have developed a new multifunctional DNA nanoflower for high specific photodynamic cancer therapy. Photodynamic therapy (PDT) is a newly emerged strategy for disease treatment, but one challenge is the non-specificity of the photosensitive molecules used. The DNA nanoflower, constructed through DNA rolling cycle amplification (RCA) reaction, contains a versatile AS1411 G-quadruplex moiety that allows for specific recognition of cancer cells and near-infrared ray based photodynamic therapy. The researchers demonstrated that the DNA nanoflower showed good selectivity toward cancer cells and had promising results in in vivo experiments. This research has been peer-reviewed and may be of interest to those studying cancer therapy and nanotechnology. [Extracted from the article]