University of Manitoba Researcher Provides New Study Findings on Mastadenovirus (Molecular insights into type I interferon suppression and enhanced pathogenicity by species B human adenoviruses B7 and B14).

A new study conducted by researchers at the University of Manitoba provides molecular insights into the suppression of the interferon signaling pathway by species B human adenoviruses B7 and B14. These strains of adenovirus are known to cause severe pneumonia with a high mortality rate. The study found that these viruses are resistant to type I interferon and suppress interferon-stimulated gene activation. The research also identified key differences in the way these viruses affect host cells, shedding light on their high pathogenicity. This study lays an important foundation for future investigations into the innate immune suppression by these highly pathogenic adenoviruses. [Extracted from the article]