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A Rare Case of Autoimmune Hemolytic Anemia Caused by Autoantibody with Mimicking Anti-D and Anti-C Specificity.
- Source :
- Clinical Laboratory; 2024, Vol. 70 Issue 7, p1392-1396, 5p
- Publication Year :
- 2024
-
Abstract
- Background: Most of the autoantibodies that cause autoimmune hemolytic anemia (AIHA) are non-specific. Autoantibodies expressing alloantibody specificity are rare. Methods: We present the case of a 4-year-old boy with no history of blood transfusion or underlying medical conditions who developed AIHA caused by autoantibody with mimicking anti-D and anti-C specificity. Results: Following treatment with methylprednisolone sodium succinate and transfusion of red blood cells with negative antigens for D and C, along with administration of human immunoglobulin, the patient’s condition gradually improved. He was ultimately discharged with a good prognosis. Conclusions: This report highlights a rare case of AIHA characterized by autoantibody with mimicking anti-D and anti-C specificity. Treatments of these patients could be antigen-negative red blood cells, glucocorticoid and immunoglobulin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14336510
- Volume :
- 70
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Clinical Laboratory
- Publication Type :
- Academic Journal
- Accession number :
- 178448470
- Full Text :
- https://doi.org/10.7754/Clin.Lab.2023.231028