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A Rare Case of Autoimmune Hemolytic Anemia Caused by Autoantibody with Mimicking Anti-D and Anti-C Specificity.

Authors :
Yang Liyan
Zhang Yu
Feng Jing
Source :
Clinical Laboratory; 2024, Vol. 70 Issue 7, p1392-1396, 5p
Publication Year :
2024

Abstract

Background: Most of the autoantibodies that cause autoimmune hemolytic anemia (AIHA) are non-specific. Autoantibodies expressing alloantibody specificity are rare. Methods: We present the case of a 4-year-old boy with no history of blood transfusion or underlying medical conditions who developed AIHA caused by autoantibody with mimicking anti-D and anti-C specificity. Results: Following treatment with methylprednisolone sodium succinate and transfusion of red blood cells with negative antigens for D and C, along with administration of human immunoglobulin, the patient’s condition gradually improved. He was ultimately discharged with a good prognosis. Conclusions: This report highlights a rare case of AIHA characterized by autoantibody with mimicking anti-D and anti-C specificity. Treatments of these patients could be antigen-negative red blood cells, glucocorticoid and immunoglobulin. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14336510
Volume :
70
Issue :
7
Database :
Complementary Index
Journal :
Clinical Laboratory
Publication Type :
Academic Journal
Accession number :
178448470
Full Text :
https://doi.org/10.7754/Clin.Lab.2023.231028