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Early MRI imaging and follow-up study in cerebral amyloid angiopathy.
- Source :
- Open Medicine; Jan2021, Vol. 16 Issue 1, p1-7, 7p, 1 Black and White Photograph, 1 Diagram, 3 Charts
- Publication Year :
- 2021
-
Abstract
- Aim-To study the imaging features of leukoaraiosis (LA) and hemorrhage in cerebral amyloid angiopathy (CAA) patients. Methods-The earliest MRI images of probable CAA patients and non-CAA patients were collected. The characteristics of LA in the two groups were analyzed. Cerebral micro bleeding (CMB), superficial siderosis (SS), and intracranial hemorrhage (ICH) were recorded in the follow-up study. The space relationship between CMB or SS and ICH was assessed. Results-We found that 10/21 (47.6%) patients had occipital prominent LA and 14/21 (66.7%) patients had subcortical punctate LA before the ICH, which was higher than that of the ones in the control group (p = 0.015 and 0.038, respectively). The recurrence rate of ICH was 100% (3/3) in patients with diffuse SS and 36.4% (4/11) in patients without. The recurrence rate of ICH was 60% (3/5) in patients with multiple-lobe CMBs and 44.4% (4/9) in those without. The location of the ICH and CMB was inconsistent. ICH occurred in the ipsilateral cerebral hemisphere of SS in three patients with diffuse SS. Conclusion-LA, diffuse SS, and multiple-lobe CMBs are important imaging characteristics of CAA, which may help make early diagnosis and predict the recurrence of ICH. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23915463
- Volume :
- 16
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Open Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 178612829
- Full Text :
- https://doi.org/10.1515/med-2021-0212