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Timing of Resection of Spinal Meningiomas and Its Influence on Quality of Life and Treatment.
- Source :
- Cancers; Jul2024, Vol. 16 Issue 13, p2336, 18p
- Publication Year :
- 2024
-
Abstract
- Simple Summary: Is the resection of spinal meningiomas in asymptomatic patients or patients with mild neurological symptoms justified? In this study, we compare the neurological outcome, quality of life, and quality of care of these patients to patients with more severe neurological symptoms. The results show that early neurosurgical intervention leads to better neurological outcomes and quality of life, contradicting a watch-and-see regime. Background: The main treatment modality for spinal meningiomas (SM) is gross total resection (GTR). However, the optimal timing of surgery, especially in cases with absent or mild neurological symptoms, remains unclear. The aim of this study is to assess the impact of early-stage resection on neurological outcome, quality of life (QoL), and quality of care. The primary objective is a favorable neurological outcome (McCormick scale 1). Methods: We retrospectively analyzed data from patients who underwent operations for SM between 2011 and 2021. Patients with mild neurological symptoms preoperatively (McCormick scale 1 and 2) were compared to those with more severe neurological symptoms (McCormick scale 3–5). Disabilities and QoL were assessed according to validated questionnaires (SF-36, ODI, NDI). Results: Age, spinal cord edema, thoracic localization, and spinal canal occupancy ratio were associated with more severe neurological symptoms (all p < 0.05). Patients presenting with mild symptoms were associated with favorable neurological outcomes (OR: 14.778 (95%CI 3.918–55.746, p < 0.001)), which is associated with shorter hospitalization, better QoL, and fewer disabilities (p < 0.05). Quality of care was comparable in both cohorts. Conclusions: Early surgical intervention for SM, before the development of severe neurological deficits, should be considered as it is associated with a favorable neurological outcome and quality of life. [ABSTRACT FROM AUTHOR]
- Subjects :
- ONCOLOGIC surgery
MENINGES
RISK assessment
MEDICAL quality control
EDEMA
HOSPITAL care
QUESTIONNAIRES
TREATMENT effectiveness
RETROSPECTIVE studies
PREOPERATIVE care
AGE distribution
DESCRIPTIVE statistics
HEALTH surveys
NEUROLOGICAL disorders
ODDS ratio
QUALITY of life
CONFIDENCE intervals
EVALUATION
DISEASE risk factors
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 20726694
- Volume :
- 16
- Issue :
- 13
- Database :
- Complementary Index
- Journal :
- Cancers
- Publication Type :
- Academic Journal
- Accession number :
- 178695917
- Full Text :
- https://doi.org/10.3390/cancers16132336