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Safety evaluation of the food enzyme lysophospholipase from the genetically modified Trichoderma reesei strain DP‐Nyc81.

Authors :
Zorn, Holger
Barat Baviera, José Manuel
Bolognesi, Claudia
Catania, Francesco
Gadermaier, Gabriele
Greiner, Ralf
Mayo, Baltasar
Mortensen, Alicja
Roos, Yrjö Henrik
Solano, Marize L. M.
Sramkova, Monika
Van Loveren, Henk
Vernis, Laurence
Andryszkiewicz, Magdalena
Liu, Yi
Lunardi, Simone
Source :
EFSA Journal; Jul2024, Vol. 22 Issue 7, p1-9, 9p
Publication Year :
2024

Abstract

The food enzyme lysophospholipase (2‐lysophosphatidylcholine acylhydrolase, EC 3.1.1.5) is produced with the genetically modified Trichoderma reesei strain DP‐Nyc81 by Genencor International B.V. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in the processing of cereals and other grains for the production of glucose syrups and other starch hydrolysates. Since residual amounts of food enzyme–total organic solids are removed during these food manufacturing processes, dietary exposure was not calculated and toxicological studies were considered unnecessary. A search for the identity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that the risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
18314732
Volume :
22
Issue :
7
Database :
Complementary Index
Journal :
EFSA Journal
Publication Type :
Academic Journal
Accession number :
178738072
Full Text :
https://doi.org/10.2903/j.efsa.2024.8936