Research on Cell Membrane Described by a Researcher at University of California (Focal adhesion kinase signaling - tumor vulnerabilities and clinical opportunities).

A recent research article titled "Focal adhesion kinase signaling - tumor vulnerabilities and clinical opportunities" discusses the role of focal adhesion kinase (FAK) in cell adhesion and its implications in cancer. FAK is a protein kinase that is activated by integrin receptor binding to extracellular matrix proteins. The article highlights the importance of FAK in cell motility, survival, and gene expression, as well as its association with tumor development and decreased survival in pancreatic and ovarian cancers. The researchers also discuss the potential of FAK inhibitors as a therapeutic strategy for targeting drug resistance in ovarian cancer. The article provides valuable insights into the mechanisms of FAK activation and signaling, as well as its potential as a target for combinatorial therapies. [Extracted from the article]