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Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases.

Authors :
Dong, Wen-sheng
Hu, Can
Hu, Min
Gao, Yi-peng
Hu, Yu-xin
Li, Kang
Ye, Yun-jia
Zhang, Xin
Source :
Cell Communication & Signaling; 8/5/2024, Vol. 22 Issue 1, p1-12, 12p
Publication Year :
2024

Abstract

Modern human society is burdened with the pandemic of cardiovascular and metabolic diseases. Metrnl is a widely distributed secreted protein in the body, involved in regulating glucose and lipid metabolism and maintaining cardiovascular system homeostasis. In this review, we present the predictive and therapeutic roles of Metrnl in various cardiovascular and metabolic diseases, including atherosclerosis, ischemic heart disease, cardiac remodeling, heart failure, hypertension, chemotherapy-induced myocardial injury, diabetes mellitus, and obesity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1478811X
Volume :
22
Issue :
1
Database :
Complementary Index
Journal :
Cell Communication & Signaling
Publication Type :
Academic Journal
Accession number :
178835943
Full Text :
https://doi.org/10.1186/s12964-024-01767-8