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The Etiology of Kidney Failure in Indonesia: A Multicenter Study in Tertiary-Care Centers in Jakarta.
- Source :
- Annals of Global Health; 2023, Vol. 89 Issue 1, p1-13, 13p
- Publication Year :
- 2023
-
Abstract
- Background: Despite a large number of patients requiring dialysis, the etiology of kidney failure is poorly documented in Indonesia. With the aim to reduce the disease burden, it is essential to obtain more insight in the etiology of chronic kidney disease (CKD). Objective(s): In the present study, we attempted to investigate the primary renal disease of kidney failure patients from five tertiary-care centers in Jakarta. Methods: This is a multicenter, cross-sectional study of kidney failure patients receiving kidney replacement therapy (KRT), from December 2021 to July 2022. We recruited patients aged ≥18 years, had been receiving dialysis for at least three months or a kidney transplantation. Findings: This study included 1,152 patients treated with hemodialysis (68.1%), peritoneal dialysis (7.5%), and kidney transplantation (24.4%). At the start of KRT, the median (interquartile-range [IQR]) age was 48 [37–58] years with low eGFR (median [IQR]: 5.9 [4.0–8.34] ml/minute/1.73 m<superscript>2</superscript>). Hypertension was the main comorbidity (74.2%), followed by diabetes mellitus (30.1%). The major primary kidney disease was diabetic kidney disease (27.2%), followed by glomerulonephritis (13.0%), hypertension (11.5%), and urolithiasis (10.3%). Lupus nephritis was the common underlying etiology of secondary glomerulonephritis (91%). A high rate of unknown cause (31.1%) was also observed. Conclusions: Our results suggest that diabetic kidney disease is the leading cause of kidney failure in Jakarta, followed by glomerulonephritis. This study highlights the need for a better approach on primary prevention of diabetes mellitus as well as to better recognize glomerulonephritis at earlier stage might have a significant impact on reduction of the rate of kidney failure in Indonesia. [ABSTRACT FROM AUTHOR]
- Subjects :
- KIDNEY failure
CROSS-sectional method
PERITONEAL dialysis
KIDNEY transplantation
THERAPEUTICS
RENAL replacement therapy
LUPUS nephritis
RESEARCH funding
SEX distribution
HYPERTENSION
URINARY calculi
TERTIARY care
AGE distribution
HEMODIALYSIS
DESCRIPTIVE statistics
GLOMERULONEPHRITIS
RESEARCH
KIDNEYS
GLOMERULAR filtration rate
DIABETES
Subjects
Details
- Language :
- English
- ISSN :
- 22149996
- Volume :
- 89
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Annals of Global Health
- Publication Type :
- Academic Journal
- Accession number :
- 178987425
- Full Text :
- https://doi.org/10.5334/aogh.4071