Researchers from Baylor University College of Medicine Report Recent Findings in Central Nervous System Tumors (Toxicity Profile of High-dose Methotrexate In Young Children With Central Nervous System Tumors).

The article focuses on the toxicity profile of high-dose methotrexate (HD-MTX) in young children with central nervous system tumors. Topics include the incidence of delayed methotrexate clearance, the frequency of severe mucositis, neutropenia, and thrombocytopenia, and the overall safety of HD-MTX with appropriate supportive care.