"Method For Analyzing Steroid By Liquid Chromatograph Mass Spectrometry" in Patent Application Approval Process (USPTO 20240264178).

A patent application by inventors from Shimadzu Corporation has been made available online for a method of analyzing steroid compounds in a sample using liquid chromatograph mass spectrometry (LC/MS). The method involves dividing the sample into multiple liquid fractions, treating each fraction differently, mixing the fractions together, and analyzing the mixed sample solution with a liquid chromatograph mass spectrometer. This method aims to shorten the analysis time for steroid compounds in a sample. The inventors propose using a solid-phase extraction column to divide the sample into liquid fractions and suggest the use of an organic acid or organic acid salt in the solvent of the mixed sample solution. [Extracted from the article]