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New Findings from La Trobe University in the Area of HIV/AIDS Described (Modelling Role of Protective and Nonprotective Hla Allele Inducing Different Hiv Infection Outcomes).

Source :
AIDS Weekly; 9/2/2024, p66-66, 1p
Publication Year :
2024

Abstract

A study conducted by La Trobe University in Bundoora, Australia, explores the role of human leukocyte antigens (HLA) in determining different outcomes of HIV infection. The research uses mathematical modeling and analysis of virus inhibition assay data to estimate the efficiency of CD8+ cells in lysing infected cells. The study finds that variations in HLA alleles, which are associated with different lysing rates, contribute to observed differences in infection outcomes. This research provides a potential mechanistic explanation for the varying outcomes of HIV infection induced by protective and non-protective HLA alleles. [Extracted from the article]

Details

Language :
English
ISSN :
15324524
Database :
Complementary Index
Journal :
AIDS Weekly
Publication Type :
Periodical
Accession number :
179327359