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New Findings from La Trobe University in the Area of HIV/AIDS Described (Modelling Role of Protective and Nonprotective Hla Allele Inducing Different Hiv Infection Outcomes).
- Source :
- AIDS Weekly; 9/2/2024, p66-66, 1p
- Publication Year :
- 2024
-
Abstract
- A study conducted by La Trobe University in Bundoora, Australia, explores the role of human leukocyte antigens (HLA) in determining different outcomes of HIV infection. The research uses mathematical modeling and analysis of virus inhibition assay data to estimate the efficiency of CD8+ cells in lysing infected cells. The study finds that variations in HLA alleles, which are associated with different lysing rates, contribute to observed differences in infection outcomes. This research provides a potential mechanistic explanation for the varying outcomes of HIV infection induced by protective and non-protective HLA alleles. [Extracted from the article]
- Subjects :
- CD antigens
CD8 antigen
SEXUALLY transmitted diseases
HIV infections
HIV
Subjects
Details
- Language :
- English
- ISSN :
- 15324524
- Database :
- Complementary Index
- Journal :
- AIDS Weekly
- Publication Type :
- Periodical
- Accession number :
- 179327359