Recent Advances in Pathophysiology and Therapeutic Approaches in Epilepsy.

This document is a summary of a special issue of the journal Brain Sciences on recent advances in the pathophysiology and therapeutic approaches in epilepsy. The document highlights the global impact of epilepsy, with over 65 million people affected worldwide. It emphasizes the need for a deeper understanding of the biochemical, structural, physiological, and molecular changes in epileptic brains to develop novel therapeutic targets and treatment options. The special issue includes twelve papers, including research articles, review articles, and a systematic review, covering topics such as drug-resistant epilepsy, neuroinflammation, post-traumatic epilepsy, surgical treatments, status epilepticus, self-limited focal epilepsy, transition readiness, epilepsy networks, and interictal spikes. The articles aim to expand our understanding of epilepsy and contribute to the development of new treatment approaches. [Extracted from the article]