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Analysis of Emerging Therapeutic Approaches for Treating DMD.

Authors :
Venugopal C. S.
Asha K. R.
Prakash B. R.
Source :
International Research Journal of Innovations in Engineering & Technology; Aug2024, Vol. 8 Issue 8, p264-267, 4p
Publication Year :
2024

Abstract

Muscular dystrophy, also known as Duchenne muscular dystrophy (DMD), is a fatal muscle disorder, changes to the DMD gene be the cause of this disease, DMD primarily impacts boys during childhood. For DMD there was no treatment available up until, in recent years, a range of curative approaches to Muscular Dystrophy have been under research; a few among them are development of corticosteroids, viral vector mediated gene therapy, exon skipping, etc. exon-skipping is the one of the optimistic approaches for correcting DMD, this therapy's main aim is to transform an out-of-frame mutation to convert an out-of-frame mutation into an in-frame mutation, to change of a severe DMD phenotype into a mild phenotype by restoration of reduced dystrophin aspect. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
25813048
Volume :
8
Issue :
8
Database :
Complementary Index
Journal :
International Research Journal of Innovations in Engineering & Technology
Publication Type :
Academic Journal
Accession number :
179423379
Full Text :
https://doi.org/10.47001/IRJIET/2024.808030