New Drug Research Study Findings Have Been Reported by Investigators at Stockholm University (Screening Persistent Organic Pollutants for Effects On Testosterone and Estrogen Synthesis At Human-relevant Concentrations Using H295r Cells In...).

A recent research study conducted at Stockholm University in Sweden investigated the effects of persistent organic pollutants (POPs) on testosterone and estrogen synthesis at concentrations relevant to human exposure. The study used a human adrenocortical cell line called H295R and screened 24 POPs for their effects on viability and hormone synthesis. The results showed that some POPs can interfere with endocrine signaling at concentrations found in human blood, highlighting the need for further investigation into the toxicological mechanisms of POPs and their mixtures. The research has been peer-reviewed and published in the journal Cell Biology and Toxicology. [Extracted from the article]