Misr International University Reports Findings in Antiinfectives (Evaluation of pharmacokinetic target attainment and hematological toxicity of linezolid in pediatric patients).

A recent study conducted at Misr International University in Cairo, Egypt, evaluated the pharmacokinetic target attainment and hematological toxicity of linezolid in pediatric patients. Linezolid is commonly used to treat severe and/or resistant Gram-positive infections, but few studies have assessed its pharmacokinetic target attainment in pediatrics. The study found that linezolid's standard dosing failed to achieve its pharmacokinetic targets in approximately half of the pediatric patients included in the study. The research highlights the importance of vigilant use and monitoring of linezolid, particularly in pediatric patients with multiple risk factors. [Extracted from the article]