N-acetylcysteine as a treatment for substance use cravings: A meta-analysis (Updated August 26, 2024).

The article discusses a meta-analysis examining the efficacy of N-acetylcysteine (NAC) as a treatment for substance use disorder (SUD) cravings, suggesting it may not significantly outperform placebo. Topics discussed include the analysis of 9 randomized control trials, the high heterogeneity and potential publication bias in the results, and the varied effectiveness of NAC on different substances, particularly alcohol and tobacco.