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Diving deep toward the bottlenose dolphins' antiarterial aging secret: insight for the circulating milieu as a novel mechanism to preserve endothelial health.

Authors :
Carlini, Nicholas A.
Culver, Meral N.
Wynne, Brandi M.
Hyndman, Kelly A.
Bunsawat, Kanokwan
Source :
American Journal of Physiology: Heart & Circulatory Physiology; Sep2024, Vol. 327 Issue 3, pH639-H641, 3p
Publication Year :
2024

Abstract

The article focuses on investigating whether bottlenose dolphins' circulating factors offer protection against age-related endothelial dysfunction, drawing from their unique physiological adaptations. Topics include the impact of serum from bottlenose dolphins on endothelial function in mice, comparative vascular physiology in dolphins versus humans, and the potential for future studies to explore underlying mechanisms of endothelial protection through a multi-omics approach.

Details

Language :
English
ISSN :
03636135
Volume :
327
Issue :
3
Database :
Complementary Index
Journal :
American Journal of Physiology: Heart & Circulatory Physiology
Publication Type :
Academic Journal
Accession number :
179606467
Full Text :
https://doi.org/10.1152/ajpheart.00532.2024