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One undescribed glycoside benzofuran derivative and a new p-hydroxybenzoate glycoside from the leaves of Illicium dunnianum Tutcher.

Authors :
He, Xiao-qing
Li, Hai-bo
Li, Ting
Chen, Xin-yin
Wang, Zhen-zhong
Yao, Xin-sheng
Xiao, Wei
Yu, Yang
Source :
Natural Product Research; Sep2024, Vol. 38 Issue 18, p3130-3139, 10p
Publication Year :
2024

Abstract

One undescribed benzofuran derivative (illiciumphenolicacid A, 1) and one new phenolic glycoside (illiciumphenolicacid B, 2), together with six known compounds (3–8) were isolated from the leaves of Illicium dunnianum Tutcher. Their structures were elucidated by detailed spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR). In addition, we determined the α-glucosidase inhibitory activity of the isolates in vitro using spectrophotometric methods. Compared with the positive control acarbose (IC<subscript>50</subscript> 306.2 ± 4.1 μM), compounds 1–8 were shown to be moderate potential α-glucosidase inhibitory activity with IC<subscript>50</subscript> values in the range 380–655 μM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14786419
Volume :
38
Issue :
18
Database :
Complementary Index
Journal :
Natural Product Research
Publication Type :
Academic Journal
Accession number :
179637678
Full Text :
https://doi.org/10.1080/14786419.2023.2216348