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Researcher from Advocate Children's Hospital Provides Details of New Studies and Findings in the Area of Systolic Heart Failure (Clinical Interventions and Hemodynamic Monitoring in the Setting of Left Ventricular Systolic Heart Failure in...).

Source :
Cardiovascular Week; 9/23/2024, p580-580, 1p
Publication Year :
2024

Abstract

A recent study conducted at Advocate Children's Hospital in Oak Lawn, Illinois, aimed to investigate the effects of vasoactive medications on cardiovascular parameters in pediatric patients with decreased ejection fraction. The study utilized a physics-based computer simulator to analyze the impact of different medications and their combinations on cardiac output and systemic venous saturation. The results showed that dobutamine and milrinone, when used alone or in combination with other vasoactive agents, significantly increased cardiac output and systemic venous saturation. However, the administration of epinephrine and norepinephrine alone decreased these hemodynamic parameters. The study concluded that milrinone and dobutamine were the only medications that improved systemic oxygen delivery, but caution should be exercised due to the potential negative effects on afterload. [Extracted from the article]

Details

Language :
English
ISSN :
15436853
Database :
Complementary Index
Journal :
Cardiovascular Week
Publication Type :
Periodical
Accession number :
179743113