New Findings from Albany Medical College in Pulmonary Emphysema Provides New Insights (Succinate Dehydrogenase-complex Ii Regulates Skeletal Muscle Cellular Respiration and Contractility but Not Muscle Mass In Genetically Induced Pulmonary...).

A recent study conducted by researchers at Albany Medical College in New York has found that reduced skeletal muscle mass and oxidative capacity are common in patients with pulmonary emphysema, and are associated with higher mortality rates. The study focused on the role of succinate dehydrogenase (SDH) in muscle dysfunction and found that reduced activity of SDH is a characteristic feature of muscle changes in pulmonary emphysema. However, the study also concluded that while SDH regulates myofiber respiration in experimental pulmonary emphysema, it does not control muscle mass or other body constituents. This research provides new insights into the relationship between pulmonary emphysema and muscle function. [Extracted from the article]