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Thyroid Eye Disease and Glaucoma: A Cross-Sectional Study Comparing Clinical Characteristics and Disease Severity.

Authors :
Ghenciu, Laura Andreea
Șișu, Alina Maria
Stoicescu, Emil Robert
Dănilă, Alexandra-Ioana
Iacob, Roxana
Săndesc, Mihai-Alexandru
Hațegan, Ovidiu Alin
Source :
Medicina (1010660X); Sep2024, Vol. 60 Issue 9, p1430, 13p
Publication Year :
2024

Abstract

Background and Objectives: This study investigates the relationship between thyroid eye disease (TED) and open-angle glaucoma (OAG), focusing on disease severity and clinical features. Materials and Methods: Conducted at the Timis County Emergency Clinical Hospital, the research included 106 patients, with 53 having both conditions and 53 having only OAG. Key metrics analyzed included intraocular pressure (IOP) using a Goldmann applanation tonometer, the retinal nerve fiber layer (RNFL) thickness, and optic nerve head (ONH) characteristics evaluated using optical coherence tomography (OCT). Results: Results indicated that patients with both TED and OAG experienced a 6.09% reduction in RNFL thickness and showed more rapid disease progression, with 48.35% having active TED. The mean IOP in TED patients was 27.5 ± 4.9 mmHg, which was similar to those with only OAG. Demographic factors, including age and gender, influenced the clinical course and disease severity. Conclusions: These findings underscore the importance of specialized monitoring and treatment strategies for patients with coexisting TED and OAG to prevent vision loss. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1010660X
Volume :
60
Issue :
9
Database :
Complementary Index
Journal :
Medicina (1010660X)
Publication Type :
Academic Journal
Accession number :
179965086
Full Text :
https://doi.org/10.3390/medicina60091430