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T lymphocyte-related immune response and immunotherapy in gastric cancer (Review).
- Source :
- Oncology Letters; Nov2024, Vol. 28 Issue 5, p1-11, 11p
- Publication Year :
- 2024
-
Abstract
- Gastric cancer (GC) remains a global healthcare challenge because of its high incidence and poor prognosis. The efficacy of current chemotherapy regimens for advanced GC is limited. T cells, which have been implicated in the progression of GC, have a significant impact in the tumor microenvironment. With a more detailed understanding of the mechanisms underlying the cancer immunoediting process, immunotherapy may become a promising treatment option for patients with GC. Several clinical trials are currently investigating different mechanisms targeting the tumor immune response. The present review summarized T cell-involved immune responses and various immunotherapy strategies for GC. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17921074
- Volume :
- 28
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Oncology Letters
- Publication Type :
- Academic Journal
- Accession number :
- 180068271
- Full Text :
- https://doi.org/10.3892/ol.2024.14670