Studies from Federal Research Center Provide New Data on Nerve Tissue Proteins (Pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GK-2 in rats. Part 2. Kinetics of distribution in organs and tissues).

A recent study conducted by the Federal Research Center examined the pharmacokinetics of a compound called GK-2 in rats. The researchers aimed to understand the distribution of GK-2 in organs and tissues after intraperitoneal administration. The study found that GK-2 was present in the blood plasma for 2 hours after injection, with a half-life of 0.4 hours. The compound was detected in various organs and tissues for 1.5 to 2 hours. The researchers also observed that GK-2 was excreted more slowly from the brain compared to other organs and tissues. This study provides valuable insights into the tissue availability and distribution of GK-2, which may have implications for future clinical use. [Extracted from the article]