Findings from University of Gothenburg Provide New Insights into Heart Disease (The impact of steatotic liver disease on coronary artery disease through changes in the plasma lipidome).

A recent study conducted by researchers at the University of Gothenburg has found that steatotic liver disease, a condition characterized by the accumulation of fat in the liver, is associated with an increased risk of cardiovascular disease, specifically coronary artery disease (CAD). The study analyzed the plasma lipidome, or the profile of lipids in the blood, of 2,579 Swedish participants aged 50 to 65 years. The researchers identified several lipids that were associated with both liver steatosis and CAD, with two fatty acids, docosatrienoate (22:3n6) and 2-hydroxyarachidate, showing the highest mediating effect between the two conditions. The findings suggest that these lipids may play a role in the relationship between steatotic liver disease and CAD, and further research is needed to explore their potential as mediators alongside known risk factors. [Extracted from the article]