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Differential Efficacy of Weight Loss Interventions in Patients with Versus Without Diabetes.

Authors :
Losada-Díaz, Federico
Lizarazo-Bocanegra, Santiago
Perdomo-Lugo, Juan J.
Gutiérrez-Romero, Sebastián A.
Correa-Osio, Isabella
Mendivil, Carlos O.
Source :
Diabetes Therapy; Nov2024, Vol. 15 Issue 11, p2279-2291, 13p
Publication Year :
2024

Abstract

Obesity is both a major risk factor for diabetes and a serious comorbidity of the condition. The twin epidemics of obesity and diabetes have spread globally over the past few decades. Treatment of obesity in patients with diabetes provides a host of clinical benefits that encompass virtually all body systems. Despite this, multiple lines of evidence suggest that the efficacy of most therapies for weight loss is significantly reduced among patients with diabetes. With this background, we summarize the evidence of a differential effect of lifestyle, pharmacological, and surgical treatments for obesity in patients with existing diabetes, and explore the potential mechanisms involved in this phenomenon. This information is then used to formulate strategies to improve weight loss outcomes for patients with diabetes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
18696953
Volume :
15
Issue :
11
Database :
Complementary Index
Journal :
Diabetes Therapy
Publication Type :
Academic Journal
Accession number :
180214456
Full Text :
https://doi.org/10.1007/s13300-024-01646-y