Investigators at University of Cambridge Discuss Findings in Embryonic Stem Cells [Rna Binding Protein With Multiple Splicing (Rbpms) Promotes Contractile Phenotype Splicing In Human Embryonic Stem Cell-derived Vascular Smooth Muscle Cells].

Researchers at the University of Cambridge have conducted a study on RNA Binding Protein with Multiple Splicing (RBPMS) and its role in promoting contractile phenotype splicing in human embryonic stem cell-derived vascular smooth muscle cells. The study found that RBPMS over-expression induced splicing patterns similar to those found in contractile tissue, impacting the motility and proliferative properties of the cells. This research, funded by organizations such as the Wellcome Trust and MRC, highlights the critical role of RBPMS in establishing the contractile phenotype splicing program in human vascular smooth muscle cells. [Extracted from the article]