University Hospital Reports Findings in Eosinophilic Esophagitis (Persistent desmoglein-1 downregulation and periostin accumulation in histologic remission of eosinophilic esophagitis).

A recent study conducted at University Hospital in Munich, Germany, focused on persistent molecular alterations in pediatric patients with Eosinophilic Esophagitis (EoE) despite histologic remission. The research identified specific genes and proteins, such as desmoglein-1 and periostin, that remained dysregulated in patients with inactive EoE. The findings suggest ongoing esophageal dysregulation even after histologic remission, shedding light on inflammatory processes and tissue remodeling in EoE. For more information, readers can refer to the Journal of Allergy and Clinical Immunology. [Extracted from the article]