Researchers from Federal University Rio Grande Detail Findings in Depression (Sex-specific Gene Expression Differences In the Prefrontal Cortex of Major Depressive Disorder Individuals).

Researchers from Federal University Rio Grande conducted a study on Major Depressive Disorder (MDD) and found sex-specific gene expression differences in the prefrontal cortex of individuals with MDD. The study analyzed 263 brain samples from both sexes, identifying 1169 unique transcriptionally altered genes (TAGs) primarily in the prefrontal areas. The research suggests that disruptions in RNA processing pathways may play a crucial role in MDD. This peer-reviewed study provides valuable insights into the molecular and neuronal pathway differences between females and males in relation to MDD. [Extracted from the article]