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Modular, Scalable Total Synthesis of Neopetromin†.

Modular, Scalable Total Synthesis of Neopetromin†.

Authors :
Ogawa, Hiroshige
Nagata, Yuuya
Nakamura, Hugh
Source :
Chinese Journal of Chemistry; Dec2024, Vol. 42 Issue 23, p3023-3028, 6p
Publication Year :
2024

Abstract

Comprehensive Summary: The first total synthesis of neopetromin, featuring the highly strained Tyr C‐6‐to‐Trp N‐1' linkage, is hereby reported. This modular synthetic strategy, employing C—H arylation and Larock macrocyclization, offers a novel approach to the synthesis of various RiPPs natural product families. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1001604X
Volume :
42
Issue :
23
Database :
Complementary Index
Journal :
Chinese Journal of Chemistry
Publication Type :
Academic Journal
Accession number :
180622067
Full Text :
https://doi.org/10.1002/cjoc.202400637