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COVID-19: a multi-organ perspective.

Authors :
Amaral Guarienti, Fabiana
Budelon Gonçalves, João Ismael
Gonçalves, Júlia Budelon
Costa Xavier, Fernando Antônio
Marinowic, Daniel
Machado, Denise Cantarelli
Source :
Frontiers in Cellular & Infection Microbiology; 2024, p1-12, 12p
Publication Year :
2024

Abstract

In this mini review, we explore the complex network of inflammatory reactions incited by SARS-CoV-2 infection, which extends its reach well beyond the respiratory domain to influence various organ systems. Synthesizing existing literature, it elucidates how the hyperinflammation observed in COVID-19 patients affects multiple organ systems leading to physiological impairments that can persist over long after the resolution of infection. By exploring the systemic manifestations of this inflammatory cascade, from acute respiratory distress syndrome (ARDS) to renal impairment and neurological sequelae, the review highlights the profound interplay between inflammation and organ dysfunction. By synthesizing recent research and clinical observations, this mini review aims to provide an overview of the systemic interactions and complications associated with COVID-19, underscoring the need for an integrated approach to treatment and management. Understanding these systemic effects is crucial for improving patient outcomes and preparing for future public health challenges. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22352988
Database :
Complementary Index
Journal :
Frontiers in Cellular & Infection Microbiology
Publication Type :
Academic Journal
Accession number :
180641140
Full Text :
https://doi.org/10.3389/fcimb.2024.1425547