NMR and Mass Spectral Studies on Egarose, a Novel Heptasaccharide from Goat Milk.

Goat milk oligosaccharides have anti-inflammatory properties and are involved in the repairing process after dextran sodium sulphate induced colitis. Keeping in mind the biological importance of goat milk oligosaccharides, goat milk was analyzed for its oligosaccharide content which led to the isolation of a novel heptasaccharide, Egarose, C₄₈H₈₁O₃₆N₃. The structure of the isolated oligosaccharide was elucidated by chemical transformation, chemical degradation, ¹H, ¹³C, 2D-NMR (HSQC, TOCSY, COSY, and HMBC) and Mass spectrometry as under- ... The geometry of compound Egarose was optimized by B3LYP method and 6-31 G (d,p) basis set. [ABSTRACT FROM AUTHOR]