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Findings from Veterans Affairs Medical Center in the Area of Parkinson's Disease Described (Dopamine Loss Alters Glutamate Synapses and Transporters In the Medial Prefrontal Cortex and Anxiety-related Behaviour In a Male Mptp Rodent Model of...).

Source :
Pain & Central Nervous System Week; 11/22/2024, p351-351, 1p
Publication Year :
2024

Abstract

A study conducted at the Veterans Affairs Medical Center in Portland, Oregon, explored the relationship between dopamine loss, alterations in glutamate synapses, and anxiety-related behaviors in a rodent model of Parkinson's disease. The research found that dopamine loss led to increased anxiety-related behaviors, changes in glutamate synapses, and alterations in glutamate transporters in the medial prefrontal cortex. These findings suggest a potential link between dopamine loss, glutamate levels, and anxiety in Parkinson's disease. The study was peer-reviewed and published in the European Journal of Neuroscience. [Extracted from the article]

Details

Language :
English
ISSN :
15316394
Database :
Complementary Index
Journal :
Pain & Central Nervous System Week
Publication Type :
Periodical
Accession number :
180896269