Patent Issued for Monoclonal antibodies, compositions and methods for detecting complement factor D (USPTO 12129290).

A patent has been issued for monoclonal antibodies, compositions, and methods for detecting complement factor D by Omeros Corporation. The invention addresses the need for detection reagents and assays to measure the presence and amount of Pro-Factor D and/or mature Factor D in biological samples. The patent describes isolated antibodies that specifically bind to epitopes on human mature Factor D and Pro-Factor D, as well as kits for detecting these proteins in test samples. The invention aims to enable in vitro assessment of APC inhibition by MASP-3 inhibitors. [Extracted from the article]