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The role of multiparametric MRI in predicting lymphovascular invasion in breast cancer patients.

Authors :
Wang, Jinhua
Jing, Siqing
Yang, Zhongxian
Tan, Wanchang
Liu, Yubao
Source :
Future Oncology; 2024, Vol. 20 Issue 35, p2747-2756, 10p
Publication Year :
2024

Abstract

Background: This study aims to investigate the efficacy of multifactorial MRI in diagnosing breast cancer, specifically in the context of predicting lymphovascular invasion (LVI). Materials & methods: The patients were stratified into two groups: the primary group (100 patients) and the validation group (100 patients), based on essential characteristics. Multifactorial MRI, encompassing tumor size evaluation, diffusion coefficient assessment and dynamic contrast enhancement, was employed for patient examination. Results: Statistically significant differences were observed in tumor size, diffusion coefficient and dynamic contrast enhancement between groups with LVI (LVI+) and those without (LVI-). Key parameters were identified for predicting the degree of invasion. Conclusion: The results affirm the effectiveness of multifactorial MRI in forecasting LVI. Article highlights Innovative approach: Successfully tested the methodology of using multiparametric MRI for identifying lymphovascular invasion (LVI) indicators, offering a novel advancement in breast cancer (BC) diagnostics. Enhanced accuracy: Multiparametric MRI demonstrates superior effectiveness compared with traditional methods in predicting LVI, providing a critical tool for clinicians. Key MRI parameters: Identified three significant MRI parameters – tumor size, diffusion coefficient and dynamic contrast enhancement – that are crucial for accurately predicting LVI. Clinical Implications: Emphasizes the importance of integrating multiparametric MRI into clinical practice to enable more precise diagnostics and personalized treatment strategies for BC patients. Research recommendations: Highlights the need for further research, including larger patient cohorts and multicenter studies, to validate and refine the application of multiparametric MRI in BC diagnostics. Impact on care: The study underscores the potential of multiparametric MRI to significantly enhance the quality of care and improve prognoses for patients with BC. Study validation: The findings confirm the robustness of multiparametric MRI in comparison to traditional methods, reinforcing its value in clinical settings. Personalized treatment: Advocates for the use of MRI-derived parameters to tailor treatment strategies, improving the accuracy of treatment planning and patient outcomes. Future directions: Calls for expanded research to strengthen conclusions and explore further applications of multiparametric MRI in the oncology field. Clinical relevance: Provides compelling evidence for the integration of advanced MRI techniques into routine diagnostic protocols to better manage LVI in BC. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14796694
Volume :
20
Issue :
35
Database :
Complementary Index
Journal :
Future Oncology
Publication Type :
Academic Journal
Accession number :
180920820
Full Text :
https://doi.org/10.1080/14796694.2024.2396273