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Computational Investigation of the Hemodynamic Effects of the Location of a Re-Entry Tear in Uncomplicated Type B Aortic Dissection.

Authors :
Kim, Eunji
Chung, Sung Woon
Huh, Up
Song, Seunghwan
Lee, Chung Won
Wang, Il Jae
Song, Chanhee
Goh, Tae Sik
Park, Jong-Hwan
Ryu, Dongman
Source :
Bioengineering (Basel); Nov2024, Vol. 11 Issue 11, p1085, 16p
Publication Year :
2024

Abstract

This study aimed to examine the hemodynamic modifications in uncomplicated type B aortic dissection in relation to the location of re-entry tears using a computational fluid dynamics simulation. The geometry of uncomplicated type B aortic dissection was reconstructed using computed tomography images. Subsequently, 10 virtual models were artificially generated with re-entry tears at various locations. The simulation results indicated that most models with re-entry tears had lower pressure and wall shear stress than those without re-entry tears. The overall pressure distribution of the true lumen was greater than that of the models without re-entry tears when the re-entry tear was placed at the end of the false lumen. Furthermore, the recirculation phenomenon in the false lumen was reduced as the re-entry tear was relocated to the distal region of the aorta. To determine whether and how to perform fenestration surgery in patients with uncomplicated type B aortic dissection, these computational results can be used as supplemental indicators. However, further validation in a larger number of patients through additional investigation is necessary. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23065354
Volume :
11
Issue :
11
Database :
Complementary Index
Journal :
Bioengineering (Basel)
Publication Type :
Academic Journal
Accession number :
181168508
Full Text :
https://doi.org/10.3390/bioengineering11111085